Nginx has tons of options for handling uri requests inside a location block.

To match an exact route, use the = sign.

location = /exact-match.html {
  # do stuff here
}

To match a route prefix, just drop the =

location = /users {
  # do stuff here
}

This will match any request that starts with /users, i.e. /users/summary

You can also do regex-style pattern matching, helpful for serving up static assets:

location ~* \.(css|scss|less|)$ {
  # do stuff here
}

The ~* matches regardless of case, i.e. STYLES.CSS or styles.css. To do exact matching (case sensitive), just drop the *.